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In this issue, we have included articles related to autoantibody epitope, spreading in the pre-clinical phase of RA, autoimmunity and immunodeficiency, and some new factors in the pathogenesis of ANCA-associated vasculitis. All these articles are helpful in understanding etiopathogenesis of rheumatic diseases.
Which spinal lesions are associated with new bone formation in patients with ankylosing spondylitis, anti-TNF efficacy on radiographic progression in AS patients, role of methotrexate co-medication with TNF-inhibitors in patients with psoriatic arthritis and treat-to-target recommendations by international task force in AS and psoriatic arthritis are must read articles in spondyloarthropathy section.
To understand granulomatous diseases better, pulmonary necrotizing granulomas of unknown etiology, "Endosonography vs. conventional bronchoscopy for the
diagnosis of sarcoidosis" and "Long-term follow-up of infliximab efficacy in pulmonary and extra-pulmonary sarcoidosis" are fantastic articles.
CNS lupus is always difficult to manage, not many large studies are available; so, I have included the prevalence of NPSLE in a 3-year study of 370 patients and is there any correlation between magnetic resonance imaging findings and clinical and immunological features?
In expert opinion section, Dr. Nigil Harron has discussed about AS. In 'Do You Know'section, we are discussing "Incidence of Bladder Toxicity From Cyclophosphamide in the Treatment of Rheumatic Diseases".
Hope you will enjoy this issue.
Best wishes
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