Can you get this one?

Antardhwani<br />

Romi Shah
MD, DNB Rheumatology
Consultant Rheumatologist, Ami Rheumatology Clinic, Surat

Question:

A 50-year lady from the remote village of Rajasthan presented with history of chronic back pain with spinal stiffness was referred to rheumatology clinic as a case of ankylosing spondylitis because spinal radiographs had been reported as “bamboo spine “. Previously patient had multiple spinal MRIs and x rays, orthopedic consultations, and general physician consultations without significant benefit in symptoms. In rheumatology clinic, recent investigations showed normocytic normochromic anemia, normal renal and liver function, normal ESR and CRP and negative rheumatoid factor, anti CCP antibody and ANA. Her back pain was of mechanical in nature and no history of peripheral arthritis. No other systemic issues in medical history without any history of other medical disorders. Her clinical examination showed restricted spinal movements with modified Schober’s test of 1 cm without any signs of peripheral arthritis. Further review of previous radiographs showed ossification of the attachments of tendons and ligaments and periosteal bone formations. A radiograph of forearm was requested to confirm the diagnosis.

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Answer:

The x ray of the forearm showed interosseous membrane calcification, which was diagnostic of fluorosis. Skeletal fluorosis is endemic in certain regions of India, especially in patients from rural areas where untreated underground water is major source of water for drinking and daily use. This case highlights the importance of considering patients epidemiological scenarios with imaging finings before coming to final diagnosis.

Suggested Reading:

1. Joseph A, Rajan R, Paul J et al. The continuing crippling challenge of skeletal fluorosis–Case series and review of literature. J Clin Transl Endocrinol Case Rep.2020;24:100114.

The Indian Rheumatology Association

The Professional Organization of Clinical Immunologists and Rheumatologists In India

Dr. Vinod Ravindran

Consultant Rheumatologist, Centre for Rheumatology, Calicut, Kerala.

Email : secretary@indianrheumatology.org